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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC1
All Species:
46.06
Human Site:
T248
Identified Species:
77.95
UniProt:
P07992
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07992
NP_001974.1
297
32562
T248
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
Chimpanzee
Pan troglodytes
XP_001164747
297
32515
T248
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
Rhesus Macaque
Macaca mulatta
XP_001105868
201
21761
V175
V
L
L
I
Q
V
D
V
K
D
P
Q
Q
A
L
Dog
Lupus familis
XP_855116
294
32368
T244
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P07903
298
32951
T248
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
A
Rat
Rattus norvegicus
NP_001099698
298
32624
T248
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517592
450
49542
T400
T
V
K
S
V
N
R
T
D
S
L
T
L
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080498
289
32423
T247
T
V
K
Y
V
N
K
T
D
S
C
T
L
F
T
Zebra Danio
Brachydanio rerio
NP_001096608
342
37871
T289
T
V
K
S
V
N
K
T
D
A
M
T
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623717
241
27330
T206
T
L
S
E
L
I
K
T
Q
S
N
T
L
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791729
471
51103
T407
T
V
K
S
V
N
K
T
D
V
I
T
L
L
A
Poplar Tree
Populus trichocarpa
XP_002328427
382
43165
T244
T
V
R
R
V
N
K
T
D
V
V
T
L
G
S
Maize
Zea mays
NP_001131279
397
43604
T257
S
I
R
H
V
N
K
T
D
V
V
T
L
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MA98
410
45730
S273
S
I
R
H
V
N
K
S
D
V
V
T
L
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.3
88.5
N.A.
86.2
83.5
N.A.
47.7
N.A.
51.8
52.9
N.A.
N.A.
44.7
N.A.
37.7
Protein Similarity:
100
99.6
66.3
91.2
N.A.
91.6
89.9
N.A.
56.4
N.A.
67
68.4
N.A.
N.A.
63.2
N.A.
48.4
P-Site Identity:
100
100
0
100
N.A.
93.3
100
N.A.
80
N.A.
80
80
N.A.
N.A.
40
N.A.
80
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
100
N.A.
93.3
N.A.
80
93.3
N.A.
N.A.
53.3
N.A.
80
Percent
Protein Identity:
34.8
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
48.9
47.6
N.A.
47.3
N.A.
N.A.
P-Site Identity:
60
46.6
N.A.
40
N.A.
N.A.
P-Site Similarity:
73.3
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
86
8
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
8
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
65
0
0
0
86
0
8
0
0
0
0
0
0
% K
% Leu:
0
15
8
0
8
0
0
0
0
0
8
0
93
58
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
86
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
36
8
8
0
0
% Q
% Arg:
0
0
22
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
8
58
0
0
0
8
0
58
0
0
0
0
36
% S
% Thr:
79
0
0
0
0
0
0
86
0
0
0
93
0
0
36
% T
% Val:
8
72
0
0
86
8
0
8
0
29
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _